This year’s list of the Most Powerful Women in business is the most comprehensive on record: a single worldwide list honoring 100 women. The list’s new global scope and bigger scale recognize the nature of top executives’ work—it spans the planet—as well as the near-record number of women who are leading companies on the Fortune 500, the largest in the U.S. by revenue, and the Fortune Global 500, the largest companies in the world. In total, the list features 67 women with a CEO title, some of whom only recently stepped into the corner office. Other executives listed here who are not yet CEO of their parent companies may be in the running to claim that seat soon. Still other execs are leading some of the world’s most valuable startups. All honorees are facing a business world in flux, one that’s struck with the urgency of ongoing revolutions—whether fueled by AI, green technology, or newly emboldened workers—and tempered by a lackluster economy and geopolitical instability. The business world is demanding change, and women leaders are meeting the moment. Read more about this year's list here.